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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using COX7A2L Polyclonal antibody (11416-1-AP)

    WB analysis using 11416-1-AP (same clone as 11416-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11416-1-AP (COX7A2L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human breast cancer using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human breast cancer using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

COX7A2L Polyclonal antibody, PBS Only

COX7A2L Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11416-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS, Azide, Glycerol
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

11416-1-PBS targets COX7A2L in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag1980

Product name: Recombinant human COX7A2L protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-114 aa of BC007095

Sequence: MYYKFSGFTQKLAGAWASEAYSPQGLKPVVSTEAPPIIFATPTKLTSDSTVYDYAGKNKVPELQKFFQKADGVPVYLKRGLPDQMLYRTTMALTVGGTIYCLIALYMASQPKNK

相同性解析による交差性が予測される生物種
Full Name cytochrome c oxidase subunit VIIa polypeptide 2 like
Calculated molecular weight 114 aa, 13 kDa
Observed molecular weight 14 kDa
GenBank accession numberBC007095
Gene Symbol COX7A2L
Gene ID (NCBI) 9167
RRIDAB_2245402
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDO14548
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

Cytochrome c oxidase (COX) is the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. The mitochondrially encoded subunits function in electron transfer, and the nuclear encoded subunits may function in the regulation and assembly of the complex. COX7A2L (cytochrome c oxidase subunit 7A-related protein), also known as COX7AR or COX7RP, is an inner mitochondrial membrane protein. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. Recently it was found that DNA methylation of COX7A2L had a significant association with therapy response in patients with breast cancer. In Alzheimer's disease the expression of COX7A2L was reduced.

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