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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using CNGA2 Polyclonal antibody (23823-1-AP)

    WB analysis using 23823-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 23823-1-AP (CNGA2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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CNGA2 Polyclonal antibody

CNGA2 Polyclonal Antibody for WB, ELISA
Cat No. 23823-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

Cyclic nucleotide-gated channel alpha-2, CNG-2, CNG channel alpha-2, CNCG2, CNCA1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Positive WB detected inA431 cells, HepG2 cells, mouse brain tissue, rat brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

23823-1-AP targets CNGA2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CNGA2 fusion protein Ag19899 相同性解析による交差性が予測される生物種
Full Name cyclic nucleotide gated channel alpha 2
Calculated molecular weight 664 aa, 76 kDa
Observed molecular weight80 kDa
GenBank accession numberBC126302
Gene Symbol CNGA2
Gene ID (NCBI) 1260
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDQ16280
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Cyclic nucleotide-gated (CNG) channels are crucial for visual and olfactory transductions (PMID: 12432397). Native CNG channels are heterotetramers composed of homologous A and B subunits. The olfactory CNG channels are composed of two CNGA2 subunits, one CNGA4 and one CNGB1b subunit, each containing a cyclic nucleotide-binding domain (PMID: 22786723). CNGA2, also named as CNCA, CNCA1 and CNCG2, is the primary subunit of the olfactory CNG channel. Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. Activation of olfactory channel by cyclic nucleotides leads to a depolarization of olfactory sensory neurons.

Protocols

Product Specific Protocols
WB protocol for CNGA2 antibody 23823-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols