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- KD/KO Validated
CoraLite® Plus 488-conjugated CLIC4 Monoclonal antibody
CLIC4 Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG1
Reactivity
human, pig, rat
Applications
FC (Intra)
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1B7F9
Cat no : CL488-66343
Synonyms
Validation Data Gallery
Tested Applications
| Positive FC detected in | HeLa cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Flow Cytometry (FC) | FC : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Sample-dependent, check data in validation data gallery | |
Product Information
CL488-66343 targets CLIC4 in FC (Intra) applications and shows reactivity with human, pig, rat samples.
| Tested Reactivity | human, pig, rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CLIC4 fusion protein Ag2942 相同性解析による交差性が予測される生物種 |
| Full Name | chloride intracellular channel 4 |
| Calculated molecular weight | 253 aa, 29 kDa |
| Observed molecular weight | 29 kDa |
| GenBank accession number | BC012444 |
| Gene symbol | CLIC4 |
| Gene ID (NCBI) | 25932 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIC4 is a p53- and tumor necrosis factor alpha-regulated cytoplasmic and mitochondrial protein that belongs to the CLIC family of intracellular chloride channels. CLICs have actions distinct from traditional cell membrane chloride channels, including formation of ion channels in intracellular organelles and roles in membrane trafficking, apoptosis, and cell differentiation.
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 488 CLIC4 antibody CL488-66343 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
