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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87798-1-PBS targets Claudin 25 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | claudin-like |
| Calculated molecular weight | 229aa, 25 kDa |
| Observed molecular weight | 32 kDa |
| GenBank accession number | M_001101389 |
| Gene Symbol | hCG_1646420 |
| Gene ID (NCBI) | 644672 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | C9JDP6 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Claudin-25, also known as Claudin containing domain 1, is a tight junction protein. It plays a role in epithelial cell barrier function and ion transport regulation. Predominantly expressed in the blood-brain barrier (BBB) and myelin sheaths, it regulates paracellular permeability. It plays vital roles in maintaining neural homeostasis, and its dysregulation is linked to demyelinating diseases and certain cancers.