Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
31683-1-PBS targets CIZ1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag35418 Product name: Recombinant human CIZ1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 126-350 aa of BC021163 Sequence: FFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ 相同性解析による交差性が予測される生物種 |
| Full Name | CDKN1A interacting zinc finger protein 1 |
| Observed molecular weight | 140 kDa |
| GenBank accession number | BC021163 |
| Gene Symbol | CIZ1 |
| Gene ID (NCBI) | 25792 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9ULV3 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
CIZ1, also known as LSFR1 and ZNF356, is a nuclear protein and the binding partner of p21. The full-length CIZ1 consists of 842 amino acid (aa) residues and contains two glutamine-rich domains, three C2H2-type zinc finger motifs, one acidic domain, and one MH3 domain (PMID: 10529385). Dysregulated or point mutated CIZ1 has been implicated in neurodegenerative, autoimmune and cancer diseases.