Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
86905-1-PBS targets CGREF1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Ag35664 Product name: Recombinant human CGREF1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 24-301 aa of BC034764 Sequence: GVTRPDSEVQHQLLPNPFQPGQEQLGLLQSYLKGLGRTEVQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVDKVLETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQVENDEI 相同性解析による交差性が予測される生物種 |
| Full Name | cell growth regulator with EF-hand domain 1 |
| Calculated molecular weight | 301 aa, 32 kDa |
| Observed molecular weight | 20-22 kDa |
| GenBank accession number | BC034764 |
| Gene Symbol | CGREF1 |
| Gene ID (NCBI) | 10669 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q99674 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
CGREF1, also known as CGR11, is predicted to enable calcium ion binding activity and to be involved in negative regulation of cell population proliferation. Human GREF1 protein has 4 clustered 17-amino acid repeats within the C terminus, suggesting a structure resembling 4 alpha-helical domains interrupted by distinct turns. Northern blot analysis of rat tissues demonstrated expression of CGR11 predominantly in the whole brain and kidney, with limited expression in heart, lung, liver, and skeletal muscle and no expression in spleen and testis.