Validation Data Gallery
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Tested Applications
| Positive WB detected in | HeLa cells, SH-SY5Y cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
Product Information
17634-1-AP targets CDON in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CDON fusion protein Ag11904 相同性解析による交差性が予測される生物種 |
| Full Name | Cdon homolog (mouse) |
| Calculated molecular weight | 1287 aa, 140 kDa |
| Observed molecular weight | 190 kDa |
| GenBank accession number | BC098583 |
| Gene Symbol | CDON |
| Gene ID (NCBI) | 50937 |
| RRID | AB_10804050 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q4KMG0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Cell adhesion molecule-related/down-regulated by oncogenes (CDO), also known as CDON, is an orphan cell surface receptor belonging to the immunoglobulin superfamily. CDON possesses five Ig-like domains, with three FNIII-like repeats in the extracellular region, a transmembrane domain, and a cytoplasmic tail. CDON plays an important role in the active regulation of myogenic differentiation. The predicted molecular weight of CDON is 139 kDa, and the bands of 190 kDa may be due to glycosylation
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for CDON antibody 17634-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Microb Pathog Staphylococcal enterotoxin B exposed to pregnant rats inhibits the hedgehog signaling pathway in thymic T lymphocytes of the offspring |