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Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human skin cancer tissue using CD207/Langerin Monoclonal antibody (67788-1-Ig)

    IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human skin cancer tissue using CD207/Langerin Monoclonal antibody (67788-1-Ig)

    IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human skin cancer tissue using CD207/Langerin Monoclonal antibody (67788-1-Ig)

    IHC staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 67788-1-Ig (CD207/Langerin antibody) at dilution of 1:20000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of human skin cancer tissue using CD207/Langerin Monoclonal antibody (67788-1-Ig)

    IF Staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human skin cancer tissue using CD207/Langerin antibody (67788-1-Ig, Clone: 1H3A1 ) at dilution of 1:20000 and CoraLite®594-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-3). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of human skin cancer tissue using CD207/Langerin Monoclonal antibody (67788-1-Ig)

    IF Staining of human skin cancer using 67788-1-Ig (same clone as 67788-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human skin cancer tissue using CD207/Langerin antibody (67788-1-Ig, Clone: 1H3A1 ) at dilution of 1:20000 and CoraLite®594-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-3). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67788-1-PBS in a different storage buffer formulation.

CD207/Langerin Monoclonal antibody, PBS Only

CD207/Langerin Monoclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 67788-1-PBS
Clone No.1H3A1

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IHC, IF-P, Indirect ELISA

Synonyms

CD207, Langerin, 1H3A1, CD207 molecule, langerin, CLEC4K

Formulation:  PBS Only
PBS, Azide, Glycerol
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67788-1-PBS targets CD207/Langerin in IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen

CatNo: Ag2479

Product name: Recombinant human CD207 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-328 aa of BC022278

Sequence: MTVEKEAPDAHFTVDKQNISLWPREPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSARFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP

相同性解析による交差性が予測される生物種
Full Name CD207 molecule, langerin
Calculated molecular weight 328 aa, 37 kDa
GenBank accession numberBC022278
Gene Symbol CD207
Gene ID (NCBI) 50489
RRIDAB_2918552
Conjugate Unconjugated
Form
FormLiquid
Purification MethodProtein G purification
UNIPROT IDQ9UJ71
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

CD207 protein (also known as langerin protein) is encoded by the CD207 gene and is a type of C-type lectin receptor that is specifically expressed on the surface of LCs. It is one of the specific immunohistochemical markers of LCs (PMID: 37383183, PMID: 28109175). CD207 plays an important role in a series of non-classical antigen processing processes, such as forming Birbeck granules and processing and transporting them to local lymphoid tissue, and inducing LC maturation (PMID: 32326440).

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