Validation Data Gallery
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Tested Applications
| Positive FC detected in | human monocyte-derived mature dendritic cells, MOLT-4 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
98579-2-RR targets CD1b in FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Recombinant protein 相同性解析による交差性が予測される生物種 |
| Full Name | CD1b molecule |
| Calculated molecular weight | 333 aa, 37 kDa |
| GenBank accession number | BC069481 |
| Gene Symbol | CD1B |
| Gene ID (NCBI) | 910 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P29016 |
| Storage Buffer | PBS with 0.09% sodium azide{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
Background Information
CD1b is a ~45 kDa transmembrane glycoprotein that belongs to the MHC class I-like CD1 family. It associates non-covalently with β2-microglobulin to form a functional antigen-presenting heterodimer. CD1b is expressed on cortical thymocytes, dendritic cells (PMID: 17593659). It has the capacity to bind self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on T cells (PMID: 30399491).
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CD1b antibody 98579-2-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |