Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
98616-1-PBS targets CD15 in FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
unknow 相同性解析による交差性が予測される生物種 |
| Full Name | CD15 |
| Gene Symbol | |
| Gene ID (NCBI) | |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
CD15, also known as stage-specific embryonic antigen-1 (SSEA-1) or Lewis X (LeX), is a cell surface glycan consisting of a trisaccharide with the structure Galβ1-4[Fucα1-3]GlcNAc (PMID: 18953356). CD15 is expressed on most terminally differentiated myeloid cells, including neutrophils, eosinophils, monocytes, macrophages, mast cells, and Langerhans cells. It has also been shown to be expressed on stem cells and progenitors in the embryonic and adult nervous system, Hodgkin's lymphoma cells, and cells from a variety of solid cancers (PMID: 19185848). CD15 acts as a ligand for selectins in transendothelial migration and is involved in phagocytosis and chemotaxis (PMID: 1362195).