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Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using CCDC23 Recombinant antibody (82998-4-RR)

    IF Staining of U2OS using 82998-4-RR (same clone as 82998-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using CCDC23 antibody (82998-4-RR, Clone: 230175B2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1).CL594-Phalloidin (red). This data was developed using the same antibody clone with 82998-4-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using CCDC23 Recombinant antibody (82998-4-RR)

    IF Staining of U2OS using 82998-4-RR (same clone as 82998-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using CCDC23 antibody (82998-4-RR, Clone: 230175B2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1).CL594-Phalloidin (red). This data was developed using the same antibody clone with 82998-4-PBS in a different storage buffer formulation.

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CCDC23 Recombinant antibody, PBS Only

CCDC23 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA
Cat No. 82998-4-PBS
Clone No.230175B2

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

IF/ICC, Indirect ELISA

Synonyms

CCDC23, SVBP

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration:  100 μg, 1 mg/ml
100 μg, 1 mg/ml

¥167,000/ 100 μg

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

82998-4-PBS targets CCDC23 in IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CCDC23 fusion protein Ag33650 相同性解析による交差性が予測される生物種
Full Name coiled-coil domain containing 23
GenBank accession numberBC029427
Gene Symbol CCDC23
Gene ID (NCBI) 374969
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8N300
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

CCDC23 also known as SVBP is a small vasohibin-binding protein of 66 amino acids, and functions as a chaperone of VASH1 in vascular endothelial cells(PMID: 20736312). SVBP enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin(PMID: 29146869, 31171830). Mutations in SVBP cause Neurodevelopmental disorders with ataxia, hypotonia, and microcephaly (NEDAHM)(PMID: 30607023, 31363758).