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MUC1/CA15-3 N-terminal Polyclonal antibody

MUC1/CA15-3 N-terminal Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG







Cat no : 19976-1-AP


CA15 3, CA153, CA15-3, Carcinoma associated mucin, CD227, EMA, Episialin, H23AG, KL-6, MAM6, MUC 1, MUC1, MUC1 beta, MUC1 CT, MUC1 NT, MUC1/CA15-3 N-terminal, Mucin 1, Peanut reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated mucin

Tested Applications

Recommended dilution

Sample-dependent, check data in validation data gallery

Product Information

19976-1-AP targets MUC1/CA15-3 N-terminal in WB, IHC, CoIP applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name mucin 1, cell surface associated
Calculated molecular weight 122 kDa
Observed molecular weight 122 kDa
GenBank accession numberJ05582
Gene symbol MUC1
Gene ID (NCBI) 4582
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

MUC1 is a type I transmembrane glycoprotein expressed by various epithelial cells of female reproductive tract, lung, breast, kidney, stomach, and pancreas. MUC1 is transcribed as a large precursor gene product, and upon translation, is cleaved in the endoplasmic reticulum, yielding two subunits: the large extracellular N-terminal subunit (MUC1-N, about 120-200 kDa) and the small cytoplasmic C-terminal subunit (MUC1-C, about 23-30 kDa). Among the known mucins, MUC1 is best studied and plays crucial roles in regulating many cellular properties, including cell proliferation, apoptosis, adhesion, and invasion. MUC1 is overexpressed in a wide range of human epithelial malignancies. This antibody was raised against the N-terminal region of human MUC1, thus it recognizes the 120 kDa extracellular MUC1.



Endocr Pathol

Expression of MUC1 and CD176 (Thomsen-Friedenreich antigen) in Papillary Thyroid Carcinomas.

Authors - Xiang-Xiang Zhan

ACS Appl Mater Interfaces

Aptamer-Peptide Conjugates as Targeted Chemosensitizers for Breast Cancer Treatment.

Authors - Yan Tan

Int J Nanomedicine

Integration of Dual Targeting and Dual Therapeutic Modules Endows Self-Assembled Nanoparticles with Anti-Tumor Growth and Metastasis Functions.

Authors - Biao Chen

J Exp Clin Cancer Res

CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.

Authors - Zhi-Hong Zong

Reprod Biol Endocrinol

PMID: 29925391

Authors - Cheng Li

Hum Cell

GalNAc-T3 and MUC1, a combined predictor of prognosis and recurrence in solitary pulmonary adenocarcinoma initially diagnosed as malignant solitary pulmonary nodule (≤ 3 cm).

Authors - Qiang Xie