Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
20323-1-AP targets C4orf14 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C4orf14 fusion protein Ag14186 相同性解析による交差性が予測される生物種 |
| Full Name | chromosome 4 open reading frame 14 |
| Calculated molecular weight | 698 aa, 78 kDa |
| GenBank accession number | BC004894 |
| Gene Symbol | C4orf14 |
| Gene ID (NCBI) | 84273 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8NC60 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Nitric oxide associated-1 (NOA1), also known as C4orf14, is an evolutionarily conserved guanosine triphosphate (GTP) binding protein. It localizes predominantly to mitochondria in mammalian cells. Human NOA1 has been shown to interact with complex I of the electron transport chain and with three mitoribosomal proteins, MRPL12, MRPS27, and MRPS29, indicating that NOA1 may interact with the mitoribosome. Recent studies suggest that C4orf14 interacts with human mitochondrial nucleoids, and is involved in the biogenesis of the small mitochondrial ribosomal subunit.