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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using ADPRM Polyclonal antibody (17017-1-AP)

    WB analysis using 17017-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 17017-1-AP (C17orf48 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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ADPRM Polyclonal antibody

ADPRM Polyclonal Antibody for WB, ELISA
Cat No. 17017-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat, pig

Applications

WB, ELISA

Synonyms

C17orf48, ADPRibase Mn, ADPRibase-Mn, ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese Dependent, CDP choline phosphohydrolase

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Positive WB detected inmouse brain tissue, rat brain tissue, pig brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

17017-1-AP targets ADPRM in WB, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Reactivity human, mouse, rat, pig
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ADPRM fusion protein Ag9997 相同性解析による交差性が予測される生物種
Full Name chromosome 17 open reading frame 48
Calculated molecular weight 40 kDa
Observed molecular weight45 kDa
GenBank accession numberBC001294
Gene Symbol C17orf48
Gene ID (NCBI) 56985
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ3LIE5
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese dependent) is a manganese-dependent glycophosphatase primarily responsible for the breakdown of molecules such as ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine in the cell. The protein is predicted to be located in the cytoplasm and possesses 2',3'-cyclic nucleotide 2'-phosphodiesterase activity, manganese ion-binding activity, and pyrophosphatase activity. ADPRM plays an important role in embryonic development, particularly in the formation of the heart and lungs. In addition, ADPRM may be involved in immune cell signaling, acting as a second messenger for ADP-ribose to activate TRPM2, which in turn regulates oxidative/nitrosative stress.

Protocols

Product Specific Protocols
WB protocol for ADPRM antibody 17017-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols