Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
33627-1-PBS targets C10orf76 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38164 Product name: Recombinant human C10orf76 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 539-689 aa of NM_024541.2 Sequence: DTFLPTPSSYDELYYEIIRMHQSFDNLYSMVLRLSTNAGQWKEAASKVTHALVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRANYDTLTLKLQDGLDQYERYSEQHKEAAFFKELVRSISTNVRRNLAFHTLSQEVLLKEFSTIS 相同性解析による交差性が予測される生物種 |
| Full Name | chromosome 10 open reading frame 76 |
| Calculated molecular weight | 79kDa，689aa |
| Observed molecular weight | 70-79 kDa |
| GenBank accession number | NM_024541.2 |
| Gene Symbol | C10orf76 |
| Gene ID (NCBI) | 79591 |
| RRID | AB_3743033 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q5T2E6 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
C10orf76, also known as ARMH3 (Armadillo-like helical domain-containing protein 3), was previously reported to be a regulator of phosphatidylinositol 4-kinase beta (PI4KB, also known as PI4KIIIbeta) at the TGN. Upon cGAMP-triggered translocation, ARMH3 interacted with STING at the Golgi and recruited phosphatidylinositol 4-kinase beta (PI4KB) to synthesize PI4P, which directed STING Golgi-to-endosome trafficking via PI4P-binding proteins AP-1 and GGA2 (PMID: 39580461, 36921576).