Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
31938-1-PBS targets ARHGAP23 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag36340 Product name: Recombinant human ARHGAP23 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 500-700 aa of NM_001199417 Sequence: KVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTEDSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQDCSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSLDSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQI 相同性解析による交差性が予測される生物種 |
| Full Name | Rho GTPase activating protein 23 |
| Calculated molecular weight | 162kDa |
| Observed molecular weight | 140-150 kDa |
| GenBank accession number | NM_001199417 |
| Gene Symbol | ARHGAP23 |
| Gene ID (NCBI) | 57636 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9P227 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
ARHGAP23 (Rho GTPase Activating Protein 23) belongs to the family of Rho GTPase activating proteins. The protein functions as a GTPase-activating factor by converting Rho class GTPases into their inactive GDP-bound state. ARHGAP23 is involved in the Rho GTPase signaling pathway, affecting processes such as cytoskeletal reorganization, cell migration, and cell proliferation. In non-small cell lung cancer, the expression of ARHGAP23 is associated with tumor immune infiltration and prognosis, and its role in tumor development has attracted attention. Mutations in this gene are related to a variety of diseases, including certain types of cancer and neurological disorders.