Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
23838-1-PBS targets ANXA2R in IHC, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag20807 Product name: Recombinant human C5orf39 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 1-193 aa of BC067873 Sequence: MEQHFLGCVKRAWDSAEVAPEPQPPPIVSSEDRGPWPLPLYPVLGEYSLDSCDLGLLSSPCWRLPGVYWQNGLSPGVQSTLEPSTAKPTEFSWPGTQKQQEAPVEEVGQAEEPDRLRLRQLPWSSPLHPWDRQQDTEVCDSGCLLERRHPPALQPWRHLPGFSDCLEWILRVGFAAFSVLWACCSRICGAKQP 相同性解析による交差性が予測される生物種 |
| Full Name | chromosome 5 open reading frame 39 |
| Calculated molecular weight | 193 aa, 22 kDa |
| GenBank accession number | BC067873 |
| Gene Symbol | ANXA2R |
| Gene ID (NCBI) | 389289 |
| RRID | AB_2879333 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen Affinity purified |
| UNIPROT ID | Q3ZCQ2 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
ANXA2R (annexin A2 receptor) is a receptor protein that interacts with annexin A2 (ANXA2). ANXA2R plays significant roles in various diseases. For instance, in renal cell carcinoma (RCC), high expression of ANXA2R is associated with poor prognosis. A recent study published in Nature revealed that SP140 regulates interferon mRNA stability and antiviral immunity by inhibiting a novel regulator, RESIST, which decreases the stability of Ifnb1 mRNA and thereby suppresses interferon expression. Notably, RESIST is the orthologue of human ANXA2R. This finding highlights the crucial role of ANXA2R in cellular signaling and immune responses.