Validation Data Gallery
Tested Applications
| Positive WB detected in | HeLa cells, Jurkat cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
30517-1-AP targets AK6 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | AK6 fusion protein Ag29330 相同性解析による交差性が予測される生物種 |
| Full Name | AK6 |
| Calculated molecular weight | 20 kDa |
| Observed molecular weight | 20-24 kDa |
| GenBank accession number | NM_016283.4 |
| Gene Symbol | AK6 |
| Gene ID (NCBI) | 102157402 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y3D8 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Adenylate Kinase 6 (AK6), also known as human coilin-interacting nuclear ATPase protein (hCINAP), is a unique enzyme that belongs to the adenylate kinase family. It is encoded by the AK6 gene located on chromosome 5q13.2. AK6 is a dual-activity enzyme, possessing both adenylate kinase and ATPase activities. The protein is involved in various biological processes, including gene transcription, ribosome quality control, embryonic development, cellular senescence, metabolism, proliferation, apoptosis, DNA damage response, and inflammation. It is also implicated in tumor development and has been explored as a potential drug target for cancer and neurodegenerative diseases.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for AK6 antibody 30517-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |