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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

30713-1-PBS targets ADRB3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ADRB3 fusion protein Ag31466 相同性解析による交差性が予測される生物種
Full Name adrenergic, beta-3-, receptor
Calculated molecular weight 44 kDa
Observed molecular weight44-50 kDa
GenBank accession numberNM_000025
Gene Symbol ADRB3
Gene ID (NCBI) 155
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP13945
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

Beta-3 adrenergic receptor(ADRB3), a member of the G-protein-coupled receptor family, is expressed mainly in adipose tissue and is thought to contribute to lipolysis and thermogenesis. In addition, the overexpression of ADRB3 has been found in several cancer types, including breast cancer, gallbladder cancer , and colorectal cancer. More recently, the involvement of ADRB3 in the metabolic reprogramming of melanoma, the promotion of immune tolerance, and the regulation of cancer differentiation have been described. (PMID: 32514619)

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