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ADAR1 Recombinant antibody

ADAR1 Recombinant Antibody for WB, ELISA
Cat No. 85009-1-RR
Clone No.241595E8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

ADAR, DRADA, Double-stranded RNA-specific adenosine deaminase, adenosine deaminase RNA specific, 241595E8

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inHepG2 cells, HeLa cells, HEK-293T cells, A431 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

85009-1-RR targets ADAR1 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ADAR1 fusion protein Ag5609 相同性解析による交差性が予測される生物種
Full Name adenosine deaminase, RNA-specific
Calculated molecular weight 136 kDa
Observed molecular weight 110 kDa
GenBank accession numberBC038227
Gene Symbol ADAR1
Gene ID (NCBI) 103
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP55265
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an IFN inducible ∼150 kDa protein and a constitutively expressed N-terminally truncated ∼110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria (DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).

Protocols

Product Specific Protocols
WB protocol for ADAR1 antibody 85009-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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