Validation Data Gallery
Tested Applications
| Positive WB detected in | mouse kidney tissue, rat kidney tissue |
| Positive IP detected in | mouse kidney tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
16997-1-AP targets ACAD11 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag10689 Product name: Recombinant human ACAD11 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 188-538 aa of BC019607 Sequence: VEGLWNLFLPAVSGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVINGKKWWSSGAGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRLTAKI 相同性解析による交差性が予測される生物種 |
| Full Name | acyl-Coenzyme A dehydrogenase family, member 11 |
| Calculated molecular weight | 780 aa, 87 kDa |
| Observed molecular weight | 85 kDa |
| GenBank accession number | BC019607 |
| Gene Symbol | ACAD11 |
| Gene ID (NCBI) | 84129 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q709F0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
ACAD11 (Acyl-CoA Dehydrogenase Family Member 11) is a mitochondrial enzyme protein belonging to the acyl-CoA dehydrogenase (ACAD) superfamily. It participates in the mitochondrial fatty acid β-oxidation metabolic pathway, catalyzing the dehydrogenation of long-chain fatty acyl-CoA. ACAD11 is one of the key enzymes for long-chain fatty acid oxidation; its functional deficiency can lead to fatty acid metabolism disorders and insufficient energy supply. In addition, ACAD11 is involved in lipid metabolism regulation and cellular energy homeostasis maintenance, and its abnormal expression is associated with metabolic diseases such as obesity, insulin resistance, and non-alcoholic fatty liver disease. Studies have shown that ACAD11 may play a protective role in neurodegenerative diseases, participating in neuronal energy metabolism and oxidative stress defense.
Protocols
| Product Specific Protocols | |
|---|---|
| IP protocol for ACAD11 antibody 16997-1-AP | Download protocol |
| WB protocol for ACAD11 antibody 16997-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |