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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using ABR Recombinant antibody (84011-6-RR)

    WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84011-6-RR (ABR antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84011-6-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using ABR Recombinant antibody (84011-6-RR)

    WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84011-6-RR (ABR antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84011-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84011-6-RR

    Affinity and Kinetic Characterization of 84011-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84011-6-RR against Human ABR were performed. The affinity constant is 4.96 nM.

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ABR Recombinant antibody, PBS Only

ABR Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84011-6-PBS
Clone No.241121G1

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

MDB, active BCR related gene, 241121G1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

84011-6-PBS targets ABR in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ABR fusion protein Ag29522 相同性解析による交差性が予測される生物種
Full Name active BCR-related gene
Calculated molecular weight 98 kDa
Observed molecular weight97-100 kDa
GenBank accession numberNM_021962
Gene Symbol ABR
Gene ID (NCBI) 29
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ12979
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

ABR (Active breakpoint cluster region-related protein) is the only protein known in humans and mice to share high homology with BCR (68% amino acid identity). BCR(Breakpoint cluster region) gene was originally identified due to its involvement in a specific chromosomal translocation that causes the development of chronic myeloid leukemia and a subset of acute lymphoblastic leukemia. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. (PMID: 17116687, PMID: 37507586)