Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
30697-1-PBS targets ABCC10 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag33719 Product name: Recombinant human ABCC10 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1203-1492 aa of NM_001198934.1 Sequence: SSFTQTEAMLVSVERLEEYTCDLPQEPQGQPLQLGTGWLTQGGVEFQDVVLAYRPGLPNALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRVLLDGVDTSQLELAQLRSQLAIIPQEPFLFSGTVRENLDPQGLHKDRALWQALKQCHLSEVITSMGGLDGELGEGGRSLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPATLRNQPHSLFQQLLQSSQQGVPASLGGP* 相同性解析による交差性が予測される生物種 |
| Full Name | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 |
| Calculated molecular weight | 161kd |
| Observed molecular weight | ~190 kDa |
| GenBank accession number | NM_001198934.1 |
| Gene Symbol | ABCC10 |
| Gene ID (NCBI) | 89845 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q5T3U5 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
The ATP binding cassette sub-family C member 10 (ABCC10), also named MRP7, is a cellular transmembrane protein transporter and belongs to the ATP-binding cassette (ABC) family. MRP7 is a lipophilic anion pump responsible for the transport of glucuronide E(2)17betaG and can confer resistance to chemotherapy drugs (PMID: 16868766). Since it is glycosylated, the apparent molecular weight of ABCC10 could be variable, ranging from 161 kDa to 191 kDa (PMID: 23087055; PMID: 24103790; PMID: 31338999; PMID: 34631561).