Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
15353-1-AP targets AAK1 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag7496 Product name: Recombinant human AAK1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-236 aa of BC002695 Sequence: MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSG 相同性解析による交差性が予測される生物種 |
| Full Name | AP2 associated kinase 1 |
| Calculated molecular weight | 104 kDa |
| GenBank accession number | BC002695 |
| Gene Symbol | AAK1 |
| Gene ID (NCBI) | 22848 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q2M2I8 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
AAK1, also named as KIAA1048, belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It phosphorylates the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2). AAK1 may play a role in regulating aspects of clathrin-mediated endocytosis (PMID:14617351).