Recombinant Rat ORM1 protein (rFc Tag)
Species
Rat
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg9535
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Rat ORM1 protein Gln19-Pro205 (Accession# P02764) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 24614 |
| Accession | P02764 |
| PredictedSize | 47.2 kDa |
| SDS-PAGE | 55-70 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Alpha-1-acid glycoprotein 1 (AGP1), also called orosomucoid-1 (ORM1), is a glycoprotein synthesized mostly by hepatocytes and present in human plasma. ORM1 is an acute-phase reactant protein controlled by glucocorticoids, interleukin-1 and interleukin-6, and increase up to 5-50 times upon infection and/or inflammation. Anti-apoptotic effect and role as immunomodulator of ORM have been reported. ORM is an important carrier for synthetic drugs and influences their distribution and availability in the body.
References:
1. Chen, Jie et al. Organogenesis vol. 21,1 (2025): 2519614. 2. Yu, Gang et al. Scientific reports vol. 13,1 15687. 21 Sep. 2023. 3. Yan, Nana et al. Hepatology (Baltimore, Md.), 10.1097/HEP.0000000000001737. 9 Mar. 2026. 4. Kim, Young-Eun et al. Frontiers in immunology vol. 14 1148574. 8 Sep. 2023.