Recombinant Human VSIG1 protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg6740
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human VSIG1 protein Val22-Glu232 (Accession# Q86XK7) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 340547 |
| Accession | Q86XK7 |
| PredictedSize | 48.9 kDa |
| SDS-PAGE | 63-80 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
VSIG1, also known as GPA34, is a member of the junctional adhesion molecule (JAM) family. The 387-amino acid protein contains an N-terminal V-type Ig-like domain, a C2-type Ig-like domain, and a transmembrane domain. The expression of VSIG1 in the epithelial cells of stomach mucosa and testicular germ cells.
References:
1.Inoue, Yusuke et al. Cancer science vol. 108,8 (2017): 1701-1714. 2.Scanlan, Matthew J et al. Cancer immunity vol. 6 2. 12 Jan. 2006.