Recombinant Human GFRA3 protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg5897
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human GFRA3 protein Asp32-Asn374 (Accession# O60609-1) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 2676 |
| Accession | O60609-1 |
| PredictedSize | 63.9 kDa |
| SDS-PAGE | 68-85 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
GFRA3 is a receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). It mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.
References:
1. Eftang, L.L., Klajic, J., Kristensen, V.N. et al. BMC Cancer 16, 225 (2016). 2. Li, Jing et al. FEBS letters vol. 583,15 (2009): 2479-85. 3. Wheeler, Joshua J et al. Frontiers in pain research (Lausanne, Switzerland) vol. 7 1716651. 17 Mar. 2026.