Recombinant Human Hepsin protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg5042
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human Hepsin protein Arg45-Arg155 (Accession# P05981) with a rabbit IgG Fc tag at the N-terminus. |
| GeneID | 3249 |
| Accession | P05981 |
| PredictedSize | 39.0 kDa |
| SDS-PAGE | 39-48 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Hepsin is a type II membrane-associated protein and a cell surface protease. It functions directly by degrading the extracellular matrix of surrounding cells and also acts as an activator of other extracellular proteases. It has been reported to be involved in a variety of biological processes.
References:
1.Tsuji, A et al. The Journal of biological chemistry vol. 266,25 (1991): 16948-53. 2.Kazama, Y et al. The Journal of biological chemistry vol. 270,1 (1995): 66-72.