Recombinant Human PCDH17 protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg4889
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human PCDH17 protein Leu18-Pro707 (Accession# O14917-1) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 27253 |
| Accession | O14917-1 |
| PredictedSize | 100.8 kDa |
| SDS-PAGE | 100-140 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
PCDH17 may play a role in the establishment and function of specific cell-cell connections in the brain. PCDH17 promoter methylation is found to be closely associated with bladder cancer malignancy.
References:
1. Xu ZJ, et al. (2019). J Transl Med. 17(1):102. 2. Wang XB, et al. (2014). J Int Med Res. 42(2):292-9.
