Recombinant Human FGFR2(IIIb) protein (hFc Tag, Myc Tag, His Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
hFc Tag, Myc Tag, His Tag
Activity
not tested
Cat no : Eg0175
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human FGFR2(IIIb) protein Arg22-Glu378 (Accession# P21802-3) with a human IgG1 Fc tag, a Myc tag and a His tag at the C-terminus. |
| GeneID | 2263 |
| Accession | P21802-3 |
| PredictedSize | 71.1 kDa |
| SDS-PAGE | 85-115 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
FGFR2 (Fibroblast growth factor receptor 2) is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration, and apoptosis. Lig
References:
1. Vogel, Arndt et al. Annual review of medicine vol. 74 (2023): 293-306. 2. Goyal, Lipika et al. The New England journal of medicine vol. 388,3 (2023): 228-239. 3. Subbiah, Vivek et al. Cancer discovery vol. 13,9 (2023): 2012-2031. 4. Zingg, Daniel et a