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CoraLite® Plus 488 Anti-Mouse KLRG1 (2F1)

KLRG1 Monoclonal Antibody for FC

Host / Isotype

Golden Syrian Hamster / IgG

Reactivity

Mouse

Applications

FC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

2F1

Cat no : CL488-65084

Synonyms

2F1 Ag, Klrg1, MAFA, MAFA L

Validation Data Gallery

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  • Flow cytometry (FC) experiment of mouse splenocytes using CoraLite® Plus 488 Anti-Mouse KLRG1 (2F1) (CL488-65084)

    FC experiment of mouse splenocytes using CL488-65084

    1x10^6 mouse splenocytes were surface stained with 0.5 ug CoraLite® Plus 488 Anti-Mouse KLRG1 (2F1) (CL488-65084, Clone:2F1) or 0.5 ug Isotype Control, and 0.5 ug APC Anti-Mouse NK1.1 (CD161) (PK136) (APC-65138, Clone: PK136). Cells were not fixed.

Tested Applications

Positive FC detected inmouse splenocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-65084 targets KLRG1 in FC applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Host / Isotype Golden Syrian Hamster / IgG
Class Monoclonal
Type Antibody
Immunogen N/A
Full Name killer cell lectin-like receptor subfamily G, member 1
GenBank Accession NumberBC101953
Gene Symbol Klrg1
Gene ID (NCBI) 50928
RRIDAB_2919257
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAffinity purification
Storage Buffer PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).

Protocols

Product Specific Protocols
FC protocol for CL Plus 488 KLRG1 antibody CL488-65084Download protocol
Standard Protocols
Click here to view our Standard Protocols