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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated CSDE1 Polyclonal antibody

CSDE1 Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-13319

Synonyms

CSDE1, D1S155E, DKFZp779B0247, DKFZp779J1455, FLJ26882, KIAA0885, N ras upstream gene protein, NRU, Protein UNR, RP5 1000E10.3, UNR

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using CoraLite® Plus 488-conjugated CSDE1 Polyclonal ant (CL488-13319)

    IF Staining of HeLa using CL488-13319

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using CoraLite® Plus 488 CSDE1 antibody (CL488-13319) at dilution of 1:200.

Tested Applications

Positive IF detected inHeLa cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-13319 targets CSDE1 in IF applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CSDE1 fusion protein Ag4173
Full Name cold shock domain containing E1, RNA-binding
Calculated Molecular Weight 798 aa, 89 kDa
Observed Molecular Weight 89 kDa
GenBank Accession NumberBC032446
Gene Symbol CSDE1
Gene ID (NCBI) 7812
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CSDE1 (Cold shock domain-containing protein E1), also known as UNR (upstream of N-ras), is an RNA-binding protein involved in the regulation of messenger RNA stability and internal initiation of translation. It is required for internal initiation of translation of human rhinovirus RNA. UNR may be involved in translationally coupled mRNA turnover. Reduced expression of UNR impairs proliferation and differentiation of erythroid blasts. Recent study found that UNR acts as a positive or negative regulator of cell death, depending on the cell type, suggesting manipulation of UNR level may constitute a specific approach to sensitize cancer cells to anticancer treatments.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 CSDE1 antibody CL488-13319Download protocol
Standard Protocols
Click here to view our Standard Protocols