Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87659-1-PBS targets GGT1 as part of a matched antibody pair:
MP03153-1: 87659-3-PBS capture and 87659-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Eg6301 Product name: Recombinant mouse CD224/GGT1 protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 27-568 aa of NM_001305992.1 Sequence: PYTSGKPDHVYSRAAVATDAKRCSEIGRDILQEGGSVVDAAIASLLCMGLMNAHSMGIGGGLFFTIYNSTTGKVEVINAREVAPRLANTTMFNNSKDSEEGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARHGFPVGKGLAIALDKKRDVIEKTPALCEVFCRQGKVLQEGETVTMPKLADTLQILAQEGAKAFYNGSLTAQIVKDIQEAGGIMTVEDLNNYRAELIEHPMSIGLGDATLYVPSAPLSGPVLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRFAYAKRTMLGDPKFVDVSQVIRNMSSEFYATQLRARITDETTHPAAYYEPEFYLQDDGGTAHLSAVSEDGSAVAATSTINLYFGSKVLSRVSGILFNDEMDDFSSPNFINQFRVAPSPANFIKPGKQPLSSMCPSIILDKDGQVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKDIDQVVTAGLKIRHHHTEVTPTFIAVVQAVVRASGGWAAASDSRKGGEPAGY 相同性解析による交差性が予測される生物種 |
| Full Name | gamma-glutamyltransferase 1 |
| Calculated molecular weight | 62 kDa |
| Observed molecular weight | 50-61 kDa |
| GenBank accession number | NM_001305992.1 |
| Gene Symbol | Ggt1 |
| Gene ID (NCBI) | 14598 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q60928 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
GGT1 is a heterodimer composed of light chain and heavy chain, and its active site is located in the light chain. The metabolism of glutathione by GGT1 releases free glutamic acid and dipeptide cysteine-glycine, which can be hydrolyzed into cysteine and glycine by dipeptidase. In the presence of high concentration of dipeptide and some amino acids, it can also catalyze the peptide transfer reaction and transfer γ -glutamyl group to receptor amino acids to form new γ -glutamyl compounds. Participate in cysteine homeostasis, glutathione homeostasis and the transformation of leukotriene LTC4 to LTD4 (PMID:12810527).