Validation Data Gallery
Tested Applications
| Positive WB detected in | human placenta tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
86397-1-RR targets PFTK2 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Ag11448 Product name: Recombinant human PFTK2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-349 aa of BC038807 Sequence: MTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDE 相同性解析による交差性が予測される生物種 |
| Full Name | PFTAIRE protein kinase 2 |
| Calculated molecular weight | 435aa, 49 kDa |
| Observed molecular weight | 49 kDa |
| GenBank accession number | BC038807 |
| Gene Symbol | CDK15 |
| Gene ID (NCBI) | 65061 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q96Q40 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
CDK15, also known as ALS2CR7 and PFTK2, belongs to the CDK family. CDK15 is a Serine/threonine-protein kinase that acts like an anti-apoptotic protein against TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34' (PMID: 24866247). CDK15 has 5 isoforms with the molecular weights of 39 kDa and 44-49 kDa.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for PFTK2 antibody 86397-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |