Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
85136-1-PBS targets ACOX2 as part of a matched antibody pair:
MP01838-1: 85136-2-PBS capture and 85136-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Ag11778 Product name: Recombinant human ACOX2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 336-681 aa of BC047700 Sequence: KVLDYQTQQQKLFPQLAISYAFHFLAVSLLEFFQHSYTAILNQDFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGGHGYSKLSGLPSLVTKLSASCTYEGENTVLYLQVARFLVKSYLQTQMSPGSTPQRSLSPSVAYLTAPDLARCPAQRAADFLCPELYTTAWAHVAVRLIKDSVQHLQTLTQSGADQHEAWNQTTVIHLQAAKVHCYYVTVKGFTEALEKLENEPAIQQVLKRLCDLHAIHGILTNSGDFLHDAFLSGAQVDMARTAYLDLLRLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFQWAQKSPTNTQENPAYEEYIRPLLQSWRSKL 相同性解析による交差性が予測される生物種 |
| Full Name | acyl-Coenzyme A oxidase 2, branched chain |
| Calculated molecular weight | 681 aa, 77 kDa |
| Observed molecular weight | 70 kDa |
| GenBank accession number | BC047700 |
| Gene Symbol | ACOX2 |
| Gene ID (NCBI) | 8309 |
| RRID | AB_3744042 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q99424 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
ACOX2 (Acyl-CoA Oxidase 2) is a peroxisomal enzyme that catalyzes the first and rate-limiting step of branched-chain fatty acid β-oxidation, specifically targeting very long-chain fatty acids (VLCFAs) and bile acid intermediates. It plays a critical role in lipid metabolism by generating H2O2 and acetyl-CoA, thereby linking peroxisomal fatty acid oxidation to cellular energy homeostasis and redox signaling. Dysregulation of ACOX2 has been implicated in metabolic disorders, including non-alcoholic fatty liver disease (NAFLD) and certain peroxisomal biogenesis disorders, highlighting its potential as a therapeutic target for metabolic and liver-related diseases.