CoraLite® Plus 488-conjugated TROVE2 Monoclonal antibody
TROVE2 Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG2a
Reactivity
Human, Mouse, Rat
Applications
FC (Intra)
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2A4E5
Cat no : CL488-67149
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | A549 cells |
Recommended dilution
Application | Dilution |
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Flow Cytometry (FC) | FC : 0.40 ug per 10^6 cells in a 100 µl suspension |
Sample-dependent, check data in validation data gallery |
Product Information
CL488-67149 targets TROVE2 in FC (Intra) applications and shows reactivity with Human, Mouse, Rat samples.
Tested Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | TROVE2 fusion protein Ag4379 相同性解析による交差性が予測される生物種 |
Full Name | TROVE domain family, member 2 |
Calculated molecular weight | 60 kDa |
Observed molecular weight | 60 kDa |
GenBank accession number | BC036658 |
Gene symbol | TROVE2 |
Gene ID (NCBI) | 6738 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
TROVE2, also named as RO60 or RoRNP, is a 538 amino acid protein, which is localized in cytoplasmic mRNP granules containing untranslated mRNAs. TROVE2 as a RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. TROVE2 may stabilize some of these RNAs and protect them from degradation (PubMed:18056422). TROVE2 binds to endogenous Alu retroelements which are induced by type I IFN and stimulate porinflammaotry cytokine secretion.
Protocols
Product Specific Protocols | |
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FC protocol for CL Plus 488 TROVE2 antibody CL488-67149 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |