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  • KD/KO Validated

TRIP13 Polyclonal antibody

TRIP13 Polyclonal Antibody for IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, IHC, IF, CoIP, ELISA

Conjugate

Unconjugated

Cat no : 19602-1-AP

Synonyms

16E1 BP, 16E1BP, PCH2, TR interacting protein 13, TRIP 13, TRIP13



Tested Applications

Positive WB detected inHT-1080 cells, mouse testis tissue, Jurkat cells
Positive IP detected inmouse testis tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 19602-1-AP is TRIP13 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRIP13 fusion protein Ag6595 相同性解析による交差性が予測される生物種
Full Name thyroid hormone receptor interactor 13
Calculated molecular weight 49 kDa
Observed molecular weight 49 kDa
GenBank accession numberBC000404
Gene symbol TRIP13
Gene ID (NCBI) 9319
RRIDAB_10642702
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TRIP13 gene encodes thyroid receptor-interacting protein 13, that interact with thyroid hormone receptors, also known as human papillomavirus type 16 E1 protein-binding protein (16E1BP). This protein belongs to the AAA ATPase family and the PCH2 subfamily. TRIP13 gene may be one of the several playing roles in early-stage non-small cell lung cancer. TRIP13 also functions in chromosome recombination and chromosome structure development during meiosis, and it is required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation.

Protocols

Product Specific Protocols
WB protocol for TRIP13 antibody 19602-1-APDownload protocol
IP protocol for TRIP13 antibody 19602-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Sci Adv

SKP1 drives the prophase I to metaphase I transition during male meiosis.

Authors - Yongjuan Guan
humanWB

Nat Commun

TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer.

Authors - Rajat Banerjee
  • KD Validated
IF

Cell Prolif

ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression

Authors - Xu Zhou
humanIHC

Mol Oncol

TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status.

Authors - Sumit Agarwal
humanWB,IHC,IP

Cell Death Dis

TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer.

Authors - Nengquan Sheng
mouseIF

PLoS Genet

The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility.

Authors - Laura Gómez-H

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Iru (Verified Customer) (06-25-2020)

This antibody works pretty well.

  • Applications: Western Blot,
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: Fallopian tube epithelial cells
FH

Min (Verified Customer) (11-11-2019)

This is very clear and strong antibody

  • Applications: Western Blot, Immunoprecipitation,
  • Primary Antibody Dilution: 1:5000
  • Cell Tissue Type: Head and neck cancer cells
TRIP13 Antibody Western Blot,Immunoprecipitation, validation (1:5000 dilution) in Head and neck cancer cells (Cat no:19602-1-AP)
FH

Iru (Verified Customer) (06-21-2019)

This antibody doesn't work well.

  • Applications: Western Blot,
  • Primary Antibody Dilution: 1:3000
  • Cell Tissue Type: Fallopian tube epithelial cells
FH

Priyanka (Verified Customer) (12-18-2018)

  • Applications: Western Blot,