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  • KD/KO Validated

SNX17 Polyclonal antibody

SNX17 Polyclonal Antibody for IHC, IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 10275-1-AP

Synonyms

KIAA0064, SNX17, sorting nexin 17



Tested Applications

Positive WB detected inHeLa cells, mouse cerebellum tissue, human brain tissue, mouse skin tissue, mouse brain tissue
Positive IP detected inHeLa cells
Positive IHC detected inmouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

10275-1-AP targets SNX17 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, rat, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SNX17 fusion protein Ag0355 相同性解析による交差性が予測される生物種
Full Name sorting nexin 17
Calculated molecular weight 53 kDa
Observed molecular weight 50 kDa
GenBank accession numberBC002524
Gene symbol SNX17
Gene ID (NCBI) 9784
RRIDAB_2192394
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Sorting nexin 17 (SNX17, synonym: KIAA0064) is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. SNX17 does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin.

Protocols

Product Specific Protocols
WB protocol for SNX17 antibody 10275-1-APDownload protocol
IHC protocol for SNX17 antibody 10275-1-APDownload protocol
IP protocol for SNX17 antibody 10275-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Nature

A phosphoinositide conversion mechanism for exit from endosomes.

Authors - Katharina Ketel
  • KD Validated
mouseWB

Nat Cell Biol

Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail.

Authors - B?ttcher Ralph Thomas RT
  • KD Validated
humanWB

Nat Cell Biol

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.

Authors - Kerrie E McNally
humanWB

Nat Cell Biol

Recycling of autophagosomal components from autolysosomes by the recycler complex.

Authors - Chuchu Zhou
humanWB

Nat Commun

A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.

Authors - Yunkai Zhu
mouseWB

Proc Natl Acad Sci U S A

LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins.

Authors - Björn Schorch
  • KD Validated