Validation Data Gallery
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Tested Applications
| Positive WB detected in | human plasma, mouse kidney tissue |
| Positive IHC detected in | human kidney tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 5 publications below |
| IHC | See 1 publications below |
Product Information
24584-1-AP targets SLCO4C1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, rat, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag20177 Product name: Recombinant human SLCO4C1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-105 aa of BC152989 Sequence: MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRCNTPG 相同性解析による交差性が予測される生物種 |
| Full Name | solute carrier organic anion transporter family, member 4C1 |
| Calculated molecular weight | 724 aa, 79 kDa |
| Observed molecular weight | 60-85 kDa |
| GenBank accession number | BC152989 |
| Gene Symbol | SLCO4C1 |
| Gene ID (NCBI) | 353189 |
| RRID | AB_2879622 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6ZQN7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SLCO4C1 is the only OATP ( organic anion transporting polypeptide) expressed at the human kidney's basolateral side of proximal tubular cells and mediates the excretion of uremic toxins (PMID: 21656517).
Protocols
| Product Specific Protocols | |
|---|---|
| IHC protocol for SLCO4C1 antibody 24584-1-AP | Download protocol |
| WB protocol for SLCO4C1 antibody 24584-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Oncol Rep Knockdown of SLCO4C1 inhibits cell proliferation and metastasis in endometrial cancer through inactivating the PI3K/Akt signaling pathway.
| ||
World J Gastrointest Pathophysiol Evaluating the regulation of transporter proteins and P-glycoprotein in rats with cholestasis and its implication for digoxin clearance. | ||
Front Cell Dev Biol Identification and verification of a prognostic signature based on a miRNA-mRNA interaction pattern in colon adenocarcinoma | ||
Aging (Albany NY) Identification and validation of SLCO4C1 as a biological marker in hepatocellular carcinoma based on anoikis classification features |
