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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated S1PR2 Polyclonal antibody

S1PR2 Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-21180

Synonyms

AGR16, EDG 5, EDG5, Gpcr13, H218, LPB2, S1P receptor 2, S1P receptor Edg 5, S1P2, S1PR2

Validation Data Gallery

Applications:
  • IF Staining of mouse brain using CL488-21180

    IF Staining of mouse brain using CL488-21180

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite® Plus 488 S1PR2 antibody (CL488-21180) at dilution of 1:200.

  • IF Staining of mouse brain using CL488-21180

    IF Staining of mouse brain using CL488-21180

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite® Plus 488 S1PR2 antibody (CL488-21180) at dilution of 1:200.

Tested Applications

Positive IF detected inmouse brain tissue
For other applications, we recommend the unconjugated version of this antibody, 21180-1-AP

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of CL488-21180 is S1PR2 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen S1PR2 fusion protein Ag15470 相同性解析による交差性が予測される生物種
Full Name sphingosine-1-phosphate receptor 2
Calculated molecular weight 353 aa, 39 kDa
Observed molecular weight 40-50 kDa
GenBank accession numberBC069598
Gene symbol S1PR2
Gene ID (NCBI) 9294
RRIDAB_2919178
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

Background Information

S1PR2 (sphingosine-1-phosphate receptor 2), also known as as S1P2 or EDG5, is one of five G-protein-coupled receptors for sphingosine-1-phosphate (S1P), a biologically active metabolic product of sphingolipid (PMID: 18787560). S1P and its receptors have important regulatory functions in normal physiology and disease processes, particularly involving the immune, central nervous, and cardiovascular systems (PMID: 21339489). S1PR2 plays a role in acute vascular inflammation (PMID: 23723450). S1PR2 signaling is implicated in STAT3 activation (PMID: 22606352).

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 S1PR2 antibody CL488-21180Download protocol
Standard Protocols
Click here to view our Standard Protocols