Validation Data Gallery
Tested Applications
Positive WB detected in | LNCaP cells, MCF-7 cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
67508-1-Ig targets LSR in WB, ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | LSR fusion protein Ag13205 相同性解析による交差性が予測される生物種 |
Full Name | lipolysis stimulated lipoprotein receptor |
Calculated molecular weight | 71 kDa |
Observed molecular weight | 68 kDa |
GenBank accession number | BC004381 |
Gene Symbol | LSR |
Gene ID (NCBI) | 51599 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q86X29 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
LSR (lipolysis stimulated lipoprotein receptor) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids (PMID: 10224102). This remnant receptor binds both apoB- and apoE-containing lipoproteins and displays greatest affinity for TG-rich lipoproteins. Distribution of LSR causes embryonic lethality in mice, indicating that the expression of LSR is critical for liver and embryonic development (PMID: 15265030). Investigations show that LSR is a multimer consisting of α subunit (68 kDa) and β subunit (56 kDa) associated through disulfide bridges (PMID: 10224102; 19188430; 18644789).
Protocols
Product Specific Protocols | |
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WB protocol for LSR antibody 67508-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |