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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

LSR Monoclonal antibody

LSR Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1G9B7

Cat no : 67508-1-Ig

Synonyms

ILDR3, LISCH, LISCH7, LSR

Validation Data Gallery

Applications:
  • WB analysis of LNCaP using 67508-1-Ig

    WB analysis of LNCaP using 67508-1-Ig

    LNCaP cells were subjected to SDS PAGE followed by western blot with 67508-1-Ig (LSR antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

  • WB analysis of MCF-7 using 67508-1-Ig

    WB analysis of MCF-7 using 67508-1-Ig

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 67508-1-Ig (LSR antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inLNCaP cells, MCF-7 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Sample-dependent, check data in validation data gallery

Product Information

67508-1-Ig targets LSR in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen LSR fusion protein Ag13205 相同性解析による交差性が予測される生物種
Full Name lipolysis stimulated lipoprotein receptor
Calculated molecular weight 71 kDa
Observed molecular weight 68 kDa
GenBank accession numberBC004381
Gene symbol LSR
Gene ID (NCBI) 51599
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

LSR (lipolysis stimulated lipoprotein receptor) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids (PMID: 10224102). This remnant receptor binds both apoB- and apoE-containing lipoproteins and displays greatest affinity for TG-rich lipoproteins. Distribution of LSR causes embryonic lethality in mice, indicating that the expression of LSR is critical for liver and embryonic development (PMID: 15265030). Investigations show that LSR is a multimer consisting of α subunit (68 kDa) and β subunit (56 kDa) associated through disulfide bridges (PMID: 10224102; 19188430; 18644789).

Protocols

Product Specific Protocols
WB protocol for LSR antibody 67508-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols