CoraLite® Plus 488-conjugated Ins1 Monoclonal antibody

Ins1 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1

Reactivity

mouse, rat

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1H2C11

Cat no : CL488-67668

Synonyms

Ins 1, Ins1, Ins2 rs1, insulin I



Tested Applications

Positive IF detected inmouse pancreas tissue
For other applications, we recommend the unconjugated version of this antibody, 67668-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:150-1:600
Sample-dependent, check data in validation data gallery

Published Applications

IFSee 1 publications below

Product Information

CL488-67668 targets Ins1 in IF applications and shows reactivity with mouse, rat samples.

Tested Reactivity mouse, rat
Cited Reactivity mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Ins1 fusion protein Ag29988 相同性解析による交差性が予測される生物種
Full Name insulin I
Calculated molecular weight 12 kDa
GenBank accession numberNM_008386
Gene symbol Ins1
Gene ID (NCBI) 16333
RRIDAB_2919515
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

insulin I is a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. The encoded precursor protein undergoes proteolytic cleavage to produce a disulfide-linked heterodimeric functional protein that is stored in secretory granules. An increase in blood glucose levels, among others, induces the release of insulin from the secretory granules. Mice deficient in the functional hormone encoded by this gene develop diabetes mellitus.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 Ins1 antibody CL488-67668Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIF

iScience

Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP

Authors - Althea N Waldhart