CoraLite®594-conjugated IL-2 Monoclonal antibody
IL-2 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
IF
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
2F11C5
Cat no : CL594-60306
Synonyms
Validation Data Gallery
Tested Applications
| Positive IF detected in | human tonsillitis tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| Sample-dependent, check data in validation data gallery | |
Product Information
CL594-60306 targets IL-2 in IF applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | IL-2 fusion protein Ag10199 相同性解析による交差性が予測される生物種 |
| Full Name | interleukin 2 |
| Calculated molecular weight | 153 aa, 18 kDa |
| GenBank accession number | BC070338 |
| Gene symbol | IL2 |
| Gene ID (NCBI) | 3558 |
| RRID | AB_2919916 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions, including T cell proliferation, interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 IL-2 antibody CL594-60306 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
