IL-11 Monoclonal antibody
IL-11 Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
1F3A12
Cat no : 68135-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | Saos-2 supernatant cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Sample-dependent, check data in validation data gallery | |
Product Information
68135-1-Ig targets IL-11 in WB, ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | IL-11 fusion protein Ag11199 相同性解析による交差性が予測される生物種 |
| Full Name | interleukin 11 |
| Calculated molecular weight | 199 aa, 21 kDa |
| Observed molecular weight | 21 kDa |
| GenBank accession number | BC012506 |
| Gene symbol | IL11 |
| Gene ID (NCBI) | 3589 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
Interleukin-11 (IL-11) is a member of the glycoprotein-130 (GP-130) cytokines that utilizes the GP-130 signaling pathway shared by other cytokines of the same family. The most well-known role of IL-11 is in hematopoiesis because it promotes megakaryocytopoiesis, erythropoiesis, and thrombopoiesis. In recognition of these properties, human IL-11 recombinant protein (rhIL-11) is used clinically for treating chemotherapy-induced thrombocytopenia. IL-11 has extensive immunomodulatory effects, both anti- and proinflammatory.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for IL-11 antibody 68135-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
