FOXP2 Polyclonal antibody

FOXP2 Polyclonal Antibody for IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, IHC, IF, CoIP, ELISA

Conjugate

Unconjugated

Cat no : 20529-1-AP

Synonyms

CAG repeat protein 44, CAGH44, forkhead box P2, Forkhead box protein P2, FOXP2, SPCH1, TNRC10



Tested Applications

Positive WB detected inHEK-293 cells, mouse brain tissue, mouse spleen tissue
Positive IP detected inmouse spleen tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 20529-1-AP is FOXP2 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FOXP2 fusion protein Ag14391
Full Name forkhead box P2
Calculated molecular weight 80 kDa
Observed molecular weight 70-80 kDa
GenBank accession numberBC018016
Gene symbol FOXP2
Gene ID (NCBI) 93986
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

FOXP2, also named as CAGH44 or TNRC10, is a 715 amino acid protein, which is a transcription factor containing a polyglutamine tract, a zinc-finger motif, and a forkheadDNA-binding domain. The role of FOXP2 in this neurodevelopmental disorder suggests that mutations in FOXP2 could cause other neuropsychiatric disorders. FOXP2 is the first gene linked to human speech and has been the target of positive selection during recent primate evolution. FOXP2 exists several isoform with the range of molecular weight 70-80 kDa and 40-50 kDa (PMID: 15056696; PMID: 29360038).

Protocols

Product Specific Protocols
WB protocol for FOXP2 antibody 20529-1-APDownload protocol
IP protocol for FOXP2 antibody 20529-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IHC,IF,CoIP

J Cancer

Low expression of FOXP2 predicts poor survival and targets caspase-1 to inhibit cell pyroptosis in colorectal cancer.

Authors - Peng Liao
  • KD Validated
humanWB

Mol Ther Nucleic Acids

circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.

Authors - Qianru He