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  • KD/KO Validated

FBXO17 Polyclonal antibody

FBXO17 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 12844-1-AP

Synonyms

F box only protein 17, F box only protein 26, F box protein 17, FBG4, Fbx17, FBX26, FBXO17, FBXO26



Tested Applications

Positive WB detected inU-251 cells, mouse heart tissue, HepG2 cells, mouse lung tissue
Positive IHC detected inhuman heart tissue, human prostate cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells, HeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

12844-1-AP targets FBXO17 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FBXO17 fusion protein Ag3867 相同性解析による交差性が予測される生物種
Full Name F-box protein 17
Calculated molecular weight 278 aa, 31 kDa
Observed molecular weight 29-31 kDa
GenBank accession numberBC012385
Gene symbol FBXO17
Gene ID (NCBI) 115290
RRIDAB_2877889
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

FBXO17, also named as FBG4, FBX17, FBX26 and FBXO26, is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Protocols

Product Specific Protocols
WB protocol for FBXO17 antibody 12844-1-APDownload protocol
IHC protocol for FBXO17 antibody 12844-1-APDownload protocol
IF protocol for FBXO17 antibody 12844-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Front Cell Dev Biol

A Novel Signature Constructed by RNA-Binding Protein Coding Genes to Improve Overall Survival Prediction of Glioma Patients.

Authors - Zewei Tu
mouseWB

J Biol Chem

SCFFBXO17 E3 ligase modulates inflammation by regulating proteasomal degradation of glycogen synthase kinase-3β in lung epithelia.

Authors - Tomeka Suber
humanIHC

Carcinogenesis

Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma.

Authors - Rui-Chao Chai
humanWB,IHC

J Gene Med

Circ_0008717 promotes renal cell carcinoma progression by upregulating FBXO17 via targeting miR-217.

Authors - Siyao Shen
humanWB

Biosci Biotechnol Biochem

F-box protein 17 promotes glioma progression by regulating glycolysis pathway.

Authors - Chao Deng
  • KD Validated
human,mouseWB,IHC

Int J Med Sci

FBXO17 Inhibits the Wnt/β-Catenin Pathway and Proliferation of Ishikawa Cells

Authors - Zi-Meng Zheng