EXOSC7 Monoclonal antibody

EXOSC7 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2A4C6

Cat no : 68456-1-Ig

Synonyms

EAP1, EXOSC7, exosome component 7, FLJ26543, hRrp42p, KIAA0116, p8, RRP42, Rrp42p



Tested Applications

Positive WB detected inSaos-2 cells, HSC-T6 cells, Caco-2 cells, LNCaP cells, HeLa cells, HEK-293 cells, NIH/3T3 cells, 4TA cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Sample-dependent, check data in validation data gallery

Product Information

68456-1-Ig targets EXOSC7 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen EXOSC7 fusion protein Ag18322 相同性解析による交差性が予測される生物種
Full Name exosome component 7
Calculated molecular weight 291 aa, 32 kDa
Observed molecular weight35 kDa
GenBank accession numberBC012831
Gene symbol EXOSC7
Gene ID (NCBI) 23016
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. EXOSC7 also named as RRP42 or EAP1 is a 291 amino acid protein, which belongs to the RNase PH family. EXOSC7 is one of the six RNase-PH domain subunits of the exosome and required for the processing of the 7S pre-RNA.

Protocols

Product Specific Protocols
WB protocol for EXOSC7 antibody 68456-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols