CoraLite®594-conjugated DLC1 Monoclonal antibody
DLC1 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
IF
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
1G10H12
Cat no : CL594-66894
Synonyms
Validation Data Gallery
Applications:
Tested Applications
| Positive IF detected in | A375 cells |
For other applications, we recommend the unconjugated version of this antibody, 66894-1-Ig
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| Sample-dependent, check data in validation data gallery | |
Product Information
CL594-66894 targets DLC1 in IF applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | DLC1 fusion protein Ag24404 相同性解析による交差性が予測される生物種 |
| Full Name | deleted in liver cancer 1 |
| Calculated molecular weight | 171 kDa |
| Observed molecular weight | 115 kDa |
| GenBank accession number | BC054511 |
| Gene symbol | DLC1 |
| Gene ID (NCBI) | 10395 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Deleted in Liver Cancer 1 (DLC1) is a RhoGAP-containing tumor suppressor that inhibits angiogenesis by repressing VEGF production in epithelial cells. DLC1 is often down-regulated in a variety of cancers, such as those of the liver, lung, breast, stomach, brain, colon and prostate due to either genomic deletion or aberrant DNA methylation.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 DLC1 antibody CL594-66894 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
