APC Anti-Mouse CD54 (YN1/1.7.4)

CD54 Monoclonal Antibody for FC

Host / Isotype

Rat / IgG2b

Reactivity

Mouse and More (1)

Applications

FC

Conjugate

APC Fluorescent Dye

CloneNo.

YN1/1.7.4

Cat no : APC-65066

Synonyms

CD54, ICAM 1, Icam1, Ly 47, MALA 2



Tested Applications

Positive FC detected inmouse splenocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Published Applications

FCSee 1 publications below

Product Information

APC-65066 targets CD54 in FC applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Cited Reactivity mouse
Host / Isotype Rat / IgG2b
Class Monoclonal
Type Antibody
Immunogen Mouse NS-1 cells 相同性解析による交差性が予測される生物種
Full Name intercellular adhesion molecule 1
GenBank accession numberBC008626
Gene symbol Icam1
Gene ID (NCBI) 15894
RRIDAB_2882968
Conjugate APC Fluorescent Dye
Excitation/Emission maxima wavelengths650 nm / 660 nm
Form Liquid
Purification Method Affinity purification
Storage Buffer PBS with 0.1% sodium azide and a stabilizer.
Storage ConditionsStore at 2-8°C. Avoid exposure to light.

Background Information

ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).

Protocols

Product Specific Protocols
FC protocol for APC CD54 antibody APC-65066Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseFC

Small

Long-Residence Pneumonia Vaccine Developed Using PEG-Grafted Hybrid Nanovesicles from Cell Membrane Fusion of Mycoplasma and IFN-γ-Primed Macrophages.

Authors - Zhenzhen Zhang