MultiPro™ 5CFLX Anti-Human CD11b (ICRF44)
CD11b Monoclonal Antibody for Single Cell (Intra), Single Cell
Host / Isotype
Mouse / IgG1, kappa
Reactivity
Human
Applications
Conjugate
5CFLX
Barcode Sequence
CCAGTCAATAGCTAT
CloneNo.
ICRF44
Cat no : G65116-1-5C
Synonyms
Validation Data Gallery
Tested Applications
Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Positive Single Cell detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Recommended dilution
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | <0.5ug/test |
SINGLE CELL | <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
G65116-1-5C targets CD11b in Single Cell (Intra), Single Cell applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1, kappa |
Class | Oligo Conjugate |
Type | Monoclonal |
Immunogen | Rheumatoid synovial cells and human monocytes 相同性解析による交差性が予測される生物種 |
Full Name | MultiPro™ 5CFLX Anti-Human CD11b (ICRF44) |
Calculated molecular weight | 1152 aa, 127 kDa |
GenBank accession number | BC096346 |
Gene symbol | CD11b |
Gene ID (NCBI) | 3684 |
Conjugate | 5CFLX |
Full Oligo Sequence | CGGAGATGTGTATAAGAGACAGCCAGTCAATAGCTATCCCATATAAGAAA |
Barcode Sequence | CCAGTCAATAGCTAT |
Form | Liquid |
Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
Storage Conditions | 2-8°C Stable for one year after shipment. |
Background Information
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).
Protocols
MultiPro™ Cell Surface and Intracellular Staining Protocol | Download protocol |
10x Genomics Cell Surface Protein Only Staining Protocol | Download protocol |